GOURI is a skin booster that places liquid polycaprolactone (PCL) dissolved in water into the skin. Unlike a particle filler that only stacks volume in one place, it is an injection made to spread in order to complement facial wrinkles and folds.
The manufacturer is Dexlevo. The use described in the product information is to complement moderate to severe facial wrinkles and folds by placing the product from the mid to deep layers of the skin. Treatment-page information continues in the GOURI treatment information.
3-line summary
1. GOURI is Dexlevo's liquid PCL injection, placed to complement facial wrinkles and folds.
2. On the day, the area is disinfected, local anesthesia is used if needed, then injected, and bruising, redness, and swelling are observed first afterward.
3. An additional injection schedule is set for maintenance, and pregnancy, breastfeeding, anticoagulants, and immunosuppressants are exclusions from use.
The material GOURI places
PCL is a polymer long used as a medical material such as suture. GOURI is a product that makes that PCL liquid, without particles. The manufacturer states that after it spreads in the skin, it stimulates cells that produce collagen.
Particle-type PCL fillers can clog a needle or collect in one place. GOURI is a formulation dissolved in water so it can also be delivered through a thin needle.
What happens on the day of treatment
After reviewing skin condition, recent facial procedures, and medications in consultation, injection sites are decided. After disinfection, anesthesia is used if needed, and the product is placed in the planned layer. The treated area is sometimes smoothed with the fingertips.
| Step | What is done that day |
|---|---|
| Consultation | Skin, treatment history, medications, and injection sites are confirmed. |
| Anesthesia | Local anesthesia is used if needed. |
| Injection | It is placed from the mid to deep layers of the skin. |
| Immediately after | Bruising, redness, and swelling are observed, and you are told when to resume makeup and saunas. |
Treatment often does not end in a single session. The product information states that additional injection is needed to maintain improvement. Cost varies with volume, session count, and area; the factors that determine it can be confirmed in the cost information.
Reactions and recovery after treatment
Common reactions listed in the product information are bruising, redness, swelling, pain, tenderness, itching, and a nodular sensation. They are generally described as settling within 1~2 weeks. Inflammation, infection, and hypersensitivity can also occur, so if warmth increases or swelling spreads, seek evaluation through the path you were given.
Rare cases of bruising lasting several months have been reported. The manufacturer's research team is among the co-authors of this report, and the article processing charge was also supported by the manufacturer. The reported cases resolved with subsequent treatment.
If the product enters a blood vessel, tissue necrosis or vision damage can follow. Areas where vessels are concentrated, such as the eyelids and periocular area, are specifically flagged for caution in the product information. Start makeup after 12 hours. Postpone saunas and strong ultraviolet exposure for 2 weeks. Same-day combinations with laser or chemical peeling are not included in the product information. Shared precautions continue in the procedure safety information.
When looking at it alongside Rejuran and hyaluronic acid
The names come up together in the consultation room because all are injections placed in the skin. The criterion for choosing is today's material, not popularity. Rejuran information continues in the Rejuran Healer guide.
| Item | GOURI | Rejuran | Hyaluronic acid booster |
|---|---|---|---|
| Material placed | Liquid PCL | PN (polynucleotide) | Hyaluronic acid |
| What is reviewed in consultation | Wrinkles and folds; a spreading liquid | PN for skin texture | Hydration material |
| Maintenance | An additional-injection schedule is set together | Set according to product and area | Set according to product and area |
Outcomes of placing it after filler in the same site have not been separately verified in the product information. It is not mixed with other products in the same syringe.
Points to check before treatment
Asking the following as written distinguishes whether today's sites and exclusions match the product information. If the answers are left in the medical record, later reviews can use the same criteria.
- □ Whether today's product name is GOURI, and whether the manufacturer is Dexlevo
- □ Whether you are pregnant or breastfeeding, or under 19 years of age
- □ Whether you are taking anticoagulants, thrombolytics, anti-inflammatory analgesics, or immunosuppressants
- □ Whether there is a history of severe allergy, autoimmunity, keloid or hypertrophic scar, or active infection
- □ Recent facial filler, laser, or peeling schedule, and whether the injection site is the eyelids or periocular area
Frequently asked questions
Q1. Does GOURI treatment hurt?
Because a needle is used, there is a pricking sensation. Local anesthesia is used if needed, and pain and tenderness are also listed in the product information. Same-day pain intensity varies with site and volume.
Q2. How many sessions?
The number of sessions varies with volume and the number of sites. The first-session volume and the next visit timing are written together in consultation.
Q3. How long does it last?
What is seen immediately afterward is mainly swelling. Skin change is then observed over the following weeks. The timing of another injection is set after seeing the course.
Q4. Can it be received together with other procedures?
If laser or peeling would be added on the same day, the dates are split. Naming recent procedures in advance makes it easier to set the interval.
Q5. Who should avoid it?
Exclusions listed in the product information are pregnancy and breastfeeding, under 19 years of age, PCL hypersensitivity, severe allergy, bleeding tendency, use of anticoagulants or immunosuppressants, autoimmunity, and a hypertrophic-scar constitution. If any of these apply, other options are reviewed.
Results, duration, and suitability vary with individual skin condition, age, and lifestyle, and the same outcome cannot be guaranteed.
Procedures may cause temporary redness or swelling, and contraindications may apply, so please confirm these during your consultation.
This article is general information and does not replace individual medical care. Please confirm diagnosis and treatment suited to your condition during a consultation.
Source materials
- Dexlevo GOURI instructions for use (DEX-IFU-11) — full text confirmed, 2 pages. Use range (facial wrinkles and folds, mid~deep dermis), exclusions, expected reactions, makeup 12 hours, sauna and ultraviolet 2 weeks, prohibition on mixing with other products, additional injection for maintenance. This is a manufacturer document and is separate from the original Korean authorization text.
- Korean researchers, comparison of liquid PCL and PN for periocular fine wrinkles (PMID 31680395) — abstract and full-text PDF confirmed. Test product is Dexlevo liquid PCL. 30 enrolled, 12-week observation; reported reactions were mild swelling and pain. Authors stated no conflicts of interest; funding item not stated. Europe PMC retraction or expression-of-concern search at the time of review: 0.
- Prolonged bruising after liquid PCL injection (PMID 41869420) — abstract and full-text XML confirmed. Seven cases of bruising lasting several months after GOURI injection. Dexlevo research team among co-authors; article processing charge supported by the manufacturer. Reported cases resolved with subsequent treatment. Europe PMC retraction or expression-of-concern search at the time of review: 0.
- Rat study of a particle-free PCL formulation (PMID 33421287) — abstract confirmed (full text not listed in PMC). Study code DLMR01. Animal data that serve as the body-text basis for the statement that particle-type PCL can clog a needle and that a liquid formulation can be delivered through a thin needle. 12-week observation. Authors stated no conflicts of interest. The observed subjects were rats. Europe PMC retraction or expression-of-concern search at the time of review: 0.
- Overview of medical use of PCL polymer (PMID 32161484) — abstract and full-text XML confirmed. Used only for the statement that PCL has long been used as a medical material such as suture. This is a paper on particle-type PCL filler, a different formulation from GOURI. Authors advised the manufacturer of that particle product. Europe PMC retraction or expression-of-concern search at the time of review: 0.
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