When you book a Rejuran consultation in Gangnam, the first things to confirm are the name of the product being injected today and the contraindications. Rejuran is an injection that places PN (sodium polynucleotide) into the skin.
3-line summary
Healer, i, S, and HB plus have different instructions for use. Ask the name on today's syringe.
Pregnancy, breastfeeding, infected skin, anticoagulants, immunosuppressants, and sites that have received non-absorbable filler are listed as contraindications in the instructions for use.
Swelling and redness at the injection site are reported for about 1 week. If inflammation lasts longer, or an unrecognized reaction appears, seek medical care.
Ask the name of the product being injected today
Even under the same Rejuran name, the products are divided. Healer, i, and S contain PN, and the use written in the instructions for use is the same. They are described as being used to temporarily improve facial wrinkles in adults. Whether an appointment is specifically named for a site such as the eye area or a scar is confirmed from the product name and label on the day. HB plus adds hyaluronic acid and lidocaine to PN, and is described as being used to temporarily improve crow's-feet fine wrinkles in adults. The treatment page is Rejuran treatment information, and the original authorized wording is collected separately in the Rejuran Healer guide.
| Today's name | Material injected | Use written in the instructions for use |
|---|---|---|
| Healer, i, S | PN | Temporarily improve facial wrinkles in adults |
| HB plus | PN, hyaluronic acid, lidocaine | Temporarily improve crow's-feet fine wrinkles in adults |
※ The table summarizes the materials and uses written in the instructions for use. Cross-check the day's label against the instructions.
The HB plus instructions for use include lidocaine and mannitol hypersensitivity among contraindications, and state not to mix the product with others. Because blindness can occur if it enters a blood vessel, they state to avoid use near the glabella and close to the eye.
The procedure is placed slowly after disinfection
The instructions for use state that only a physician may use the product, and that it should be placed slowly after the site is disinfected. The amount placed varies with the treatment area, and after placement the site is massaged so the material spreads evenly. If the needle does not enter well, they state not to force it and to move to another site. Before opening, check the packaging for damage and the expiry date together. Injection-day discomfort can be checked in the Rejuran pain and recovery guide.
It is not placed inside a blood vessel. Use in the lips, and safety and efficacy in skin that readily forms keloids or dark pigment, are described as not confirmed in the instructions for use. At a site that has had oral herpes, the injection can bring the herpes back.
Seven items to check before injection
If any apply, that day's injection is postponed. Do not stop prescribed medicines on your own for the procedure; tell both the prescribing physician and the treating physician.
- □ Whether today's name is Healer, i, S, or HB plus
- □ Whether you are pregnant, breastfeeding, or a minor
- □ Whether there is inflammation or infection at the injection site
- □ Whether you are using anti-inflammatory analgesics, antiplatelet agents, anticoagulants, or immunosuppressants
- □ Whether you have allergic disease or autoimmune disease, and, for HB plus, lidocaine or mannitol hypersensitivity
- □ Whether non-absorbable filler, or recently placed filler, is present at that site
- □ Whom to contact if inflammation lasts more than 1 week
Cost varies with the amount placed and the number of sessions. The factors that determine it can be seen in pricing information.
Reactions after injection and when to call
The instructions for use state that applying pressure to the injection site can produce redness and swelling together with itching or pain, and that these reactions can last about 1 week. Firm lumps, color change, and cases where the expected change is weak are also described.
| Timing | Guidance written in the instructions for use |
|---|---|
| Immediately after through 1 week | Swelling, redness, itching, and pain reported |
| First 12 hours | Postpone makeup |
| Following 2 weeks | Avoid prolonged exposure to strong sunlight, saunas, severe cold, and heat |
| Seek care without delay | When inflammation lasts more than 1 week, or an unrecognized reaction appears |
The instructions for use state that safety and efficacy of long-term use beyond the period established in clinical research have not been confirmed. Shared standards are in treatment safety information.
Frequently asked questions
Q1. Does it hurt?
Pain, swelling, itching, and redness at the injection site have been reported. Whether cream anesthesia is used is decided in the same-day explanation.
Q2. How many sessions?
The instructions for use do not set a number of sessions. The next date is decided after the skin's response is observed.
Q3. How long does it last?
The instructions for use state that it is for temporary improvement. The comparison that placed Rejuran in crow's-feet wrinkles followed participants for 12 weeks.
Q4. Can it be received together?
Whether to receive another injection on the same day is decided after recovery is observed. Questions about choosing among other materials such as Juvelook continue in Rejuran vs Juvelook differences.
Q5. Who should postpone the appointment?
Items listed as contraindications in the instructions for use are pregnancy, breastfeeding, minors, infected skin, allergic or autoimmune disease, anti-inflammatory analgesics, antiplatelet agents, anticoagulants, immunosuppressants, sites that have received non-absorbable filler, and PN hypersensitivity. For HB plus, lidocaine and mannitol hypersensitivity also apply.
Results, duration, and suitability vary with individual skin condition, age, and lifestyle, and the same outcome cannot be guaranteed.
Procedures may cause temporary redness or swelling, and contraindications may apply, so please confirm these during your consultation.
This article is general information and does not replace individual medical care. Please confirm diagnosis and treatment suited to your condition during a consultation.
Sources
- Rejuran, Rejuran i, and Rejuran S instructions for use — full text confirmed (written December 2024, 제허 14-825호). Composition PN, intended use (temporary improvement of facial wrinkles in adults), contraindications, adverse effects, no makeup for 12 hours after injection, and 2-week avoidance of heat and UV are used in the body. The original text does not state salmon DNA or concentration.
- Rejuran HB plus instructions for use — full text confirmed (written December 2024, 제허 21-629호). Crow's-feet fine wrinkle use; PN, hyaluronic acid, and lidocaine; lidocaine and mannitol contraindications; prohibition on mixing with other products; and the blindness caution near the glabella and the eye are used in the body. Clinical-trial numbers and sex composition printed in the instructions are not used in the body.
- Comparative study of Rejuran (RJR) placed in crow's-feet wrinkles — abstract confirmed. 12-week follow-up. No Europe PMC retraction field. Improvement-rate figures and superiority versus the comparator are not used in the body. Not generalized to the whole face beyond the eye area.
Related reading
Sources
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