CELLINIQUE

Rejuran is a skin booster treatment that applies PN (polynucleotide) to the skin
Those interested in managing skin texture and hydration
Those considering a skin booster category treatment
Those who have been assessed as suitable during a prior consultation
Rejuran is a skin booster treatment that applies PN (polynucleotide) to the skin
Cellinique offers both Rejuran Healer and Rejuran HB Plus, and Dr. Kim Gun-woo will recommend the right product based on your individual skin condition and pain sensitivity
## Meta Data - **Title**: Rejuran Healer & HB Plus Treatment Guide | Cellinique Clinic, Gangnam Dosan-daero - **Description**: Cellinique's Rejuran is a PN (polynucleotide)-based skin booster treatment. Both Rejuran Healer and HB Plus available. Direct consultation and treatment by Dr. Kim Gun-woo. Gangnam Dosan-daero 02-6203-3434 - **Canonical**: https://www.cellinique.com/en/treatment/rejuran
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Rejuran is a skin booster treatment that applies **PN (polynucleotide)** to the skin - Cellinique offers both **Rejuran Healer** and **Rejuran HB Plus**, and Dr. Kim Gun-woo will recommend the right product **based on your individual skin condition and pain sensitivity** - A typical initial course involves about 3 sessions at 2–4 week intervals followed by maintenance, but **your actual course is determined after a consultation assessment**
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If you've been looking into dermatology treatments, chances are you've come across the name Rejuran at least once. Quite a few people have already tried it. But when it comes to understanding exactly what the treatment does, surprisingly clear information can be hard to find.
"What is PN?" "What's the difference between Rejuran Healer and HB Plus?" "Is it really painful?" "How many sessions do I need?"
Today, we'll walk you through everything about the **Rejuran** treatment offered at Cellinique — from how it works, to product differences, the treatment process, and aftercare guidelines.
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*Rejuran** is a skin booster treatment that applies **PN (Polynucleotide)** to the skin.
The key question is: what role does PN play in the skin? PN is a component designed to help organize the skin environment at the cellular level. The PN used in Rejuran is provided in a purified form and is approved for medical use in Korea.
**💡 Fact Check** > > - Rejuran's PN is a **purified polynucleotide component** > - Rejuran Healer and Rejuran HB Plus are **officially approved and marketed** as medical products in Korea > - Actual results may vary depending on the product, application method, and individual skin condition > - Product licensing and manufacturer details are available during consultation.
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Cellinique offers two main Rejuran products. Understanding each product's characteristics will help you choose the right option during your consultation.
**Features**: The most classic Rejuran formulation - **Anesthesia**: Topical numbing cream recommended before treatment - **Pain**: Some stinging sensation may occur even after numbing - **Application method**: Applied using an embossing (micro-point) technique
→ *"This tends to be chosen by those who prefer a more intensive application. However, if you're sensitive to pain, it's best to discuss this during your consultation."*
**Features**: Formulation that includes lidocaine (anesthetic) - **Anesthesia**: Built-in lidocaine for pain relief during treatment - **Pain**: Generally milder sensation compared to Healer - **Application method**: Distributed application across the skin
→ *"This is often chosen by those who are sensitive to pain or want to minimize downtime due to a busy schedule."*
⚠️ Which product is right for you is determined during a **consultation with Dr. Kim Gun-woo**.
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Rejuran is designed around PN (polynucleotide), a defined medical-grade component. Because the component itself is approved as a medical product, the formulation maintains consistency.
→ *From the patient's perspective, this means the reassurance that "what I received is a standardized product."*
Cellinique carries both **Rejuran Healer** and **Rejuran HB Plus**, so you can choose a product that matches your individual pain sensitivity and skin condition.
→ *"Many patients who were hesitant about the treatment due to pain concerns have found HB Plus to be a comfortable option. (Individual results may vary)"*
Rejuran is a treatment where the experience can vary depending on **injection placement, depth, and distribution**. That's why at Cellinique, Dr. Kim Gun-woo personally oversees everything from consultation through treatment.
→ *Some patients who have had Rejuran before have shared that "where you get it done seems to matter."*
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※ Results vary depending on individual skin condition, age, and lifestyle. Identical outcomes are not assured for everyone, and treatment suitability is determined through consultation.
An approach designed to help organize the dermal environment - Gradual changes in skin texture and hydration - A cumulative care approach over multiple sessions - Can be incorporated as part of a comprehensive skincare routine
The items above describe the **design intent and general application direction** of the treatment. Specific outcomes are not guaranteed, and individual results are assessed during a prior consultation.
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| Item | Details | |---|---| | **Treatment duration** | Approx. 20–40 minutes (varies by product and area) | | **Anesthesia** | Topical numbing cream (Healer) / Built-in lidocaine (HB Plus) | | **Downtime** | Embossing marks for about 1–2 days (varies by product and individual) | | **Onset of results** | Gradual after treatment (several weeks following initial sessions) | | **Recommended initial course** | About 3 sessions at 2–4 week intervals | | **Recommended maintenance** | Maintenance every 6 months (adjusted based on condition) | | **Indications** | Assessed during prior consultation | | **Contraindications** | Pregnancy/breastfeeding, active infections, allergies, autoimmune conditions, etc. — assessed during consultation | | **Price range** | Rejuran Healer / HB Plus priced separately — refer to the non-covered treatment pricing page / discussed during consultation | | **Consultation fee** | Provided during consultation |
⚠️ The above is general guidance. The right product and course for you is determined through a direct consultation with Dr. Kim Gun-woo.
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1. **Pre-treatment consultation** — Direct consultation with Dr. Kim Gun-woo. Assessment of skin condition, medical history, medications, and pain sensitivity 2. **Product selection** — Guidance on the most suitable option between Rejuran Healer and HB Plus 3. **Cleansing + anesthesia preparation** — Topical numbing cream (for Healer) or confirmation of built-in anesthetic 4. **Treatment application** — Applied according to skin condition and treatment area 5. **Post-treatment care guidance** — Downtime management and scheduling of the next session
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This is one of the most common questions. After Rejuran treatment, small **embossing marks** may be visible on the skin for a few days. These typically subside within 1–2 days, though individual experiences may vary.
*Within 24 hours after treatment** - Avoid washing your face or applying makeup until the time advised during consultation - Avoid irritating skincare products, heat, and excessive washing - Some swelling and redness at the treatment site is possible
*One week after treatment** - Avoid saunas, steam rooms, and intense exercise - Apply thorough sun protection - Follow the consultation guidance regarding combining other treatments or products
*Until the next session (typically 2–4 weeks apart)** - Maintain your regular skincare routine - If you notice any changes or unusual reactions, feel free to contact Cellinique
💡 *Many first-time Rejuran patients have shared: "I was surprised to see embossing marks the day after treatment, but they faded within a day or two." If you have a busy schedule, consider booking your treatment before a weekend or holiday. (Individual results may vary)*
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⚠️ **General Safety Standards**: Common side effects, emergency protocols, contraindications, and infection management standards applicable to all treatments are detailed on the [Cellinique Treatment Safety Information](/en/safety) page. This section covers considerations specific to this treatment.
This matters because Rejuran involves direct injection into the skin, and proper pre- and post-treatment care affects both results and safety. As with any medical procedure, it's helpful to be aware of the following possibilities.
*Commonly reported reactions** - Temporary swelling, redness, and embossing marks at the treatment site (most resolve within a few days) - Rarely, bruising or warmth - Very rarely, infection or allergic reactions
*Contact Cellinique immediately if you experience** - Severe swelling, warmth, or redness at the treatment site - Fever or chills - Suspected allergic reaction symptoms - Abnormal pain or sudden worsening of symptoms
*Please inform us before treatment about** - Pregnancy or breastfeeding status - Current medications (especially immunosuppressants or anticoagulants) - History of allergy to lidocaine or other anesthetic components (relevant for HB Plus) - Active infections or autoimmune disease history - Other recent treatments (interval adjustments may be needed) - History of skin allergies or sensitivities
⚠️ This page provides general information and does not replace medical diagnosis or prescription. Whether this treatment is suitable for you should be confirmed through a direct consultation with Dr. Kim Gun-woo.
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※ Suitability is determined only through a prior consultation. The following are general use cases for reference.
Those interested in managing skin texture and hydration - Those considering a skin booster category treatment - Those who have been assessed as suitable during a prior consultation
*The treatment may not be suitable if you** - Are pregnant or breastfeeding - Have an active infection - Have an allergy to lidocaine or other anesthetic components (HB Plus exclusion or consultation required) - Have a history of autoimmune or blood disorders - Have recently undergone major surgery or significant medical procedures
→ If any of the above apply, **please let us know during your consultation**. We'll assess treatment eligibility and discuss alternatives together.
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Cellinique is an anti-aging and regenerative aesthetics clinic located on Dosan-daero in Gangnam. We have consistently offered skin booster treatments and carry **both Rejuran Healer and HB Plus**, allowing patients to choose the option that best fits their individual condition.
*Dr. Kim Gun-woo's Background** - Board-certified specialist in Laboratory Medicine - Experienced in skin booster treatments (including Rejuran Healer and HB Plus)
At Cellinique, Dr. Kim Gun-woo **personally oversees every step from consultation through treatment and post-care**. Drawing on extensive experience with skin booster treatments, we provide a seamless, start-to-finish care experience.
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### Q1. Should I choose Rejuran Healer or HB Plus? The two products differ in formulation, built-in anesthesia, and other factors. **Rejuran Healer** is the classic formulation, while **Rejuran HB Plus** includes lidocaine (anesthetic) for pain relief during treatment. Dr. Kim Gun-woo will recommend the right option based on your pain sensitivity and skin condition during consultation.
### Q2. Is it very painful? Perceived pain varies depending on the product and anesthesia option. Topical numbing cream or the lidocaine-infused product (HB Plus) can help minimize discomfort, but individual experiences vary, so it's difficult to say it's completely painless. If you're sensitive to pain, please let us know during your consultation.
### Q3. How many sessions are needed to see results? A common approach is an **initial course of about 3 sessions at 2–4 week intervals**, followed by maintenance treatments. However, the actual number of sessions depends on your skin condition and care goals, so we'll outline a personalized course during your first consultation.
### Q4. Can I go to work right after the treatment? Rejuran may leave embossing marks that are visible for a few days after treatment. These typically fade within 1–2 days, but if you have important plans, it's more convenient to schedule treatment before a weekend or holiday.
### Q5. Can I combine this with other treatments? Combining with other treatments requires adjustment based on the type of treatment, intervals, and your individual condition. We plan these together during your consultation.
### Q6. Are there any side effects? Common reactions may include temporary swelling, embossing marks, redness, and rarely bruising. In very rare cases, infection or allergic reactions may occur. If you experience any unusual reactions after treatment, please contact Cellinique immediately.
### Q7. Can I just come in for a consultation? Absolutely. Since choosing between Healer and HB Plus is best decided through a consultation, we warmly welcome consultation-only visits. Contact us at 02-6203-3434 or via KakaoTalk.
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*Cellinique Clinic** - 📍 2F & B1, Yeonseung Building, 228 Dosan-daero, Gangnam-gu, Seoul - 📞 02-6203-3434 - 🕐 Mon–Fri 10:00–19:00 / Last Saturday of each month 10:00–16:30 - 🚇 10-minute walk from Apgujeong Station or Hakdong Station - 🅿️ Valet parking available
*[Phone Consultation]** **[KakaoTalk Consultation]** **[Online Booking]**
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Rejuran is designed around PN (polynucleotide), a defined medical-grade component. Because the component itself is approved as a medical product, the formulation maintains consistency.
Cellinique carries both Rejuran Healer and Rejuran HB Plus, so you can choose a product that matches your individual pain sensitivity and skin condition.
Rejuran is a treatment where the experience can vary depending on injection placement, depth, and distribution. That's why at Cellinique, Dr. Kim Gun-woo personally oversees everything from consultation through treatment.
Direct consultation with Dr. Kim Gun-woo. Assessment of skin condition, medical history, medications, and pain sensitivity
Guidance on the most suitable option between Rejuran Healer and HB Plus
Topical numbing cream (for Healer) or confirmation of built-in anesthetic
Applied according to skin condition and treatment area
During consultation, we review your current health, medications, allergies, pregnancy or breastfeeding status, and previous procedures.
Follow the procedure-specific guidance on irritation, heat, alcohol, exercise, and sun exposure, and contact the clinic if you notice an unexpected symptom.
Preparation and aftercare vary by procedure and individual health status. Please follow the instructions given during your consultation.
Consulting physician · Dr. Kim Gun-woo · Director, Laboratory Medicine specialist
The two products differ in formulation, built-in anesthesia, and other factors. Rejuran Healer is the classic formulation, while Rejuran HB Plus includes lidocaine (anesthetic) for pain relief during treatment. Dr. Kim Gun-woo will recommend the right option based on your pain sensitivity and skin condition during consultation.
Perceived pain varies depending on the product and anesthesia option. Topical numbing cream or the lidocaine-infused product (HB Plus) can help minimize discomfort, but individual experiences vary, so it's difficult to say it's completely painless. If you're sensitive to pain, please let us know during your consultation.
A common approach is an initial course of about 3 sessions at 2–4 week intervals, followed by maintenance treatments. However, the actual number of sessions depends on your skin condition and care goals, so we'll outline a personalized course during your first consultation.
Rejuran may leave embossing marks that are visible for a few days after treatment. These typically fade within 1–2 days, but if you have important plans, it's more convenient to schedule treatment before a weekend or holiday.
Combining with other treatments requires adjustment based on the type of treatment, intervals, and your individual condition. We plan these together during your consultation.
Common reactions may include temporary swelling, embossing marks, redness, and rarely bruising. In very rare cases, infection or allergic reactions may occur. If you experience any unusual reactions after treatment, please contact Cellinique immediately.
Absolutely. Since choosing between Healer and HB Plus is best decided through a consultation, we warmly welcome consultation-only visits. Contact us at 02-6203-3434 or via KakaoTalk.
For the shared standards on side effects, emergency response, contraindications, and infection control that apply to every Cellinique treatment, please refer to the Cellinique Treatment Safety Guide. This page covers information specific to this treatment.
View Treatment Safety GuideExplore other options in the same category that are often compared alongside this treatment.

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